Lymphoma

Lymphoma

What is Lymphoma?

Lymphoma is a type of blood cancer that begins in the lymphatic system, which is part of the body’s immune system.

It affects lymphocytes (a type of white blood cell) that help fight infections.

The lymphatic system includes:

  • Lymph nodes (neck, armpit, groin)

  • Spleen

  • Thymus

  • Bone marrow

Main Types of Lymphoma

🔹 1. Hodgkin Lymphoma (HL)

🔹 2. Non-Hodgkin Lymphoma (NHL)

Common Symptoms

  • Painless swelling of lymph nodes (neck, armpit, groin)

  • Persistent fever

  • Night sweats

  • Unexplained weight loss

  • Fatigue

  • Itching

  • Shortness of breath (if chest nodes enlarged)

⚠️ Swollen lymph nodes that persist for more than 2–3 weeks should be evaluated.

Risk Factors

  • Weak immune system

  • Autoimmune diseases

  • Certain infections (EBV, HIV, H. pylori)

  • Family history

  • Exposure to certain chemicals

  • Increasing age (varies by type)

Diagnosis

  • Physical examination

  • Lymph node biopsy (confirmatory test)

  • Blood tests

  • PET-CT scan

  • Bone marrow biopsy (if needed)

Stages of Lymphoma

  • Stage 1: Single lymph node area

  • Stage 2: Multiple nodes on same side of diaphragm

  • Stage 3: Nodes on both sides of diaphragm

  • Stage 4: Spread to organs (liver, bone marrow, lungs)

Treatment Options

Treatment depends on type and stage:

🔹 Chemotherapy

Main treatment

🔹 Immunotherapy

Common in many lymphomas

🔹 Targeted Therapy

🔹 Radiation Therapy

🔹 Stem Cell / Bone Marrow Transplant